As noted previously on this list, I recently purchased a new laptop, which is intended to run both Linux and Windows. On the Windows side, I need to guard against viruses and other forms of malware. Whatever solution I put in place has to be accessible with a screen reader. I have some system administration experience (with my own machines and, occasionally, helping others - almost entirely under Linux), so I'll take the obvious precautions - keeping the system and applications up to date, only installing software from reputable sources, etc. In other words, I won't make the obvious mistakes that people who don't know any better tend to make. Currently, Windows Defender is running by default. In the reviews I've read, it has been criticized for its virus detection accuracy, but those reviews aren't necessarily recent. What are others doing and recommending at the moment?